Response to antiretroviral therapy in occult hepatitis B and HIV co-infection in West Africa.
Identifieur interne : 000563 ( Main/Exploration ); précédent : 000562; suivant : 000564Response to antiretroviral therapy in occult hepatitis B and HIV co-infection in West Africa.
Auteurs : David Chadwick [Royaume-Uni] ; Alastair Stanley ; Stephen Sarfo ; Lambert Appiah ; Michael Ankcorn ; Geraldine Foster ; Uli Schwab ; Richard Phillips ; Anna M. GerettiSource :
- AIDS (London, England) [ 1473-5571 ] ; 2013.
Descripteurs français
- KwdFr :
- Agents antiVIH (usage thérapeutique), Antigènes de surface du virus de l'hépatite B (sang), Charge virale (), Co-infection, Femelle, Ghana (épidémiologie), Humains, Hépatite B (immunologie), Hépatite B (traitement médicamenteux), Hépatite B (épidémiologie), Indice de masse corporelle, Infections à VIH (immunologie), Infections à VIH (traitement médicamenteux), Infections à VIH (épidémiologie), Inhibiteurs de la transcriptase inverse (usage thérapeutique), Lamivudine (usage thérapeutique), Mâle, Numération des lymphocytes CD4, Prévalence, Résultat thérapeutique, Évolution de la maladie.
- MESH :
- immunologie : Hépatite B, Infections à VIH.
- sang : Antigènes de surface du virus de l'hépatite B.
- traitement médicamenteux : Hépatite B, Infections à VIH.
- usage thérapeutique : Agents antiVIH, Inhibiteurs de la transcriptase inverse, Lamivudine.
- épidémiologie : Ghana, Hépatite B, Infections à VIH.
- Charge virale, Co-infection, Femelle, Humains, Indice de masse corporelle, Mâle, Numération des lymphocytes CD4, Prévalence, Résultat thérapeutique, Évolution de la maladie.
- Wicri :
- geographic : Ghana.
English descriptors
- KwdEn :
- Anti-HIV Agents (therapeutic use), Body Mass Index, CD4 Lymphocyte Count, Coinfection, Disease Progression, Female, Ghana (epidemiology), HIV Infections (drug therapy), HIV Infections (epidemiology), HIV Infections (immunology), Hepatitis B (drug therapy), Hepatitis B (epidemiology), Hepatitis B (immunology), Hepatitis B Surface Antigens (blood), Humans, Lamivudine (therapeutic use), Male, Prevalence, Reverse Transcriptase Inhibitors (therapeutic use), Treatment Outcome, Viral Load (drug effects).
- MESH :
- chemical , blood : Hepatitis B Surface Antigens.
- chemical , therapeutic use : Anti-HIV Agents, Lamivudine, Reverse Transcriptase Inhibitors.
- geographic , epidemiology : Ghana.
- drug effects : Viral Load.
- drug therapy : HIV Infections, Hepatitis B.
- epidemiology : HIV Infections, Hepatitis B.
- immunology : HIV Infections, Hepatitis B.
- Body Mass Index, CD4 Lymphocyte Count, Coinfection, Disease Progression, Female, Humans, Male, Prevalence, Treatment Outcome.
Abstract
This study evaluated the outcome of first-line antiretroviral therapy among 35 Ghanaians with occult HBV/HIV co-infection, comparing them over 2 years to 120 patients with HBsAg+ HBV/HIV co-infection and 230 patients without HBV co-infection. Increases in CD4 cell count and BMI were similar, whereas elevations of hepatic transaminases were more frequent in both the occult HBV and HBsAg+ patients. Occult HBV/HIV co-infection appears not to impact adversely on response to antiretroviral therapy in Ghana.
DOI: 10.1097/QAD.0b013e3283589879
PubMed: 22874516
Affiliations:
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Le document en format XML
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Geretti</name></author></analytic><series><title level="j">AIDS (London, England)</title><idno type="eISSN">1473-5571</idno><imprint><date when="2013" type="published">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anti-HIV Agents (therapeutic use)</term><term>Body Mass Index</term><term>CD4 Lymphocyte Count</term><term>Coinfection</term><term>Disease Progression</term><term>Female</term><term>Ghana (epidemiology)</term><term>HIV Infections (drug therapy)</term><term>HIV Infections (epidemiology)</term><term>HIV Infections (immunology)</term><term>Hepatitis B (drug therapy)</term><term>Hepatitis B (epidemiology)</term><term>Hepatitis B (immunology)</term><term>Hepatitis B Surface Antigens (blood)</term><term>Humans</term><term>Lamivudine (therapeutic use)</term><term>Male</term><term>Prevalence</term><term>Reverse Transcriptase Inhibitors (therapeutic use)</term><term>Treatment Outcome</term><term>Viral Load (drug effects)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Agents antiVIH (usage thérapeutique)</term><term>Antigènes de surface du virus de l'hépatite B (sang)</term><term>Charge virale ()</term><term>Co-infection</term><term>Femelle</term><term>Ghana (épidémiologie)</term><term>Humains</term><term>Hépatite B (immunologie)</term><term>Hépatite B (traitement médicamenteux)</term><term>Hépatite B (épidémiologie)</term><term>Indice de masse corporelle</term><term>Infections à VIH (immunologie)</term><term>Infections à VIH (traitement médicamenteux)</term><term>Infections à VIH (épidémiologie)</term><term>Inhibiteurs de la transcriptase inverse (usage thérapeutique)</term><term>Lamivudine (usage thérapeutique)</term><term>Mâle</term><term>Numération des lymphocytes CD4</term><term>Prévalence</term><term>Résultat thérapeutique</term><term>Évolution de la maladie</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Hepatitis B Surface Antigens</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-HIV Agents</term><term>Lamivudine</term><term>Reverse Transcriptase Inhibitors</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Ghana</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Viral Load</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>HIV Infections</term><term>Hepatitis B</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>HIV Infections</term><term>Hepatitis B</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Hépatite B</term><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>HIV Infections</term><term>Hepatitis B</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Antigènes de surface du virus de l'hépatite B</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Hépatite B</term><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Agents antiVIH</term><term>Inhibiteurs de la transcriptase inverse</term><term>Lamivudine</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Ghana</term><term>Hépatite B</term><term>Infections à VIH</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Body Mass Index</term><term>CD4 Lymphocyte Count</term><term>Coinfection</term><term>Disease Progression</term><term>Female</term><term>Humans</term><term>Male</term><term>Prevalence</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Charge virale</term><term>Co-infection</term><term>Femelle</term><term>Humains</term><term>Indice de masse corporelle</term><term>Mâle</term><term>Numération des lymphocytes CD4</term><term>Prévalence</term><term>Résultat thérapeutique</term><term>Évolution de la maladie</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Ghana</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This study evaluated the outcome of first-line antiretroviral therapy among 35 Ghanaians with occult HBV/HIV co-infection, comparing them over 2 years to 120 patients with HBsAg+ HBV/HIV co-infection and 230 patients without HBV co-infection. Increases in CD4 cell count and BMI were similar, whereas elevations of hepatic transaminases were more frequent in both the occult HBV and HBsAg+ patients. Occult HBV/HIV co-infection appears not to impact adversely on response to antiretroviral therapy in Ghana.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country></list><tree><noCountry><name sortKey="Ankcorn, Michael" sort="Ankcorn, Michael" uniqKey="Ankcorn M" first="Michael" last="Ankcorn">Michael Ankcorn</name><name sortKey="Appiah, Lambert" sort="Appiah, Lambert" uniqKey="Appiah L" first="Lambert" last="Appiah">Lambert Appiah</name><name sortKey="Foster, Geraldine" sort="Foster, Geraldine" uniqKey="Foster G" first="Geraldine" last="Foster">Geraldine Foster</name><name sortKey="Geretti, Anna M" sort="Geretti, Anna M" uniqKey="Geretti A" first="Anna M" last="Geretti">Anna M. Geretti</name><name sortKey="Phillips, Richard" sort="Phillips, Richard" uniqKey="Phillips R" first="Richard" last="Phillips">Richard Phillips</name><name sortKey="Sarfo, Stephen" sort="Sarfo, Stephen" uniqKey="Sarfo S" first="Stephen" last="Sarfo">Stephen Sarfo</name><name sortKey="Schwab, Uli" sort="Schwab, Uli" uniqKey="Schwab U" first="Uli" last="Schwab">Uli Schwab</name><name sortKey="Stanley, Alastair" sort="Stanley, Alastair" uniqKey="Stanley A" first="Alastair" last="Stanley">Alastair Stanley</name></noCountry><country name="Royaume-Uni"><noRegion><name sortKey="Chadwick, David" sort="Chadwick, David" uniqKey="Chadwick D" first="David" last="Chadwick">David Chadwick</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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